We applied our in-house workflow; published ChIP-seq datasets obtained from studies in human neuroblastoma cell lines, which carried (COG-N-415, LA-N-5, and NB-1643) or lacked (NB-69) genomic amplifications of the MYCN as described [29], were subjected to rigorous bioinformatics processing (see Materials and Methods). Here, MYCN is linked to neuroblastoma.