A further study of tissue from 13 treatment-naïve patients with resectable NSCLC used cytometry by time-of-flight and IMC to describe a population of CD8+PD-L1+ tumour-infiltrating T-cells with low levels of expression of PD-1, CD103, GZMB and IFN-γ [69]. This evidence concerns the gene CD274 and non-small cell lung carcinoma.