This analysis confirmed increased CHRM3 mRNA levels in colon cancer compared to adjacent normal colon; median CHRM3 transcript levels were elevated in 286 adenocarcinomas compared to 41 normal colon samples [2.528 vs. 1.272 transcripts per million, respectively (p = 0.002)] (Figure 1A). The gene discussed is CHRM3; the disease is adenocarcinoma.