Similarly, Zhou et al. reported that both the AHI and oxygen desaturation index (ODI) were positively associated with levels of carcinoembryonic antigen (CEA), which is used for detecting CRC (particularly in individuals with a history of BMI/obesity, smoking, or inadequate glycemic management) [26]. Here, CEACAM5 is linked to obesity due to melanocortin 4 receptor deficiency.