TP53 and Mobius syndrome: According to the latest World Health Organization (WHO) classification in 2021, MBs can be classified as WNT MB, Sonic hedgehog (SHH) MB (TP53 mutated or TP53 wild-type), and non-WNT/SHH Group 3 (Gr3) and Group 4 (Gr4) MBs [2,5].