Using RNA immunoprecipitation followed by qPCR, the authors showed that NKX2-1-AS1 acts as a decoy to NKX2-1, preventing its binding to the CD274 promoter and thus negatively regulating endogenous PD-L1, limiting immune system evasion of lung adenocarcinoma cells [70]. The gene discussed is CD274; the disease is lung adenocarcinoma.