Due to Gd-EOB-DTPA-enhanced MRI demonstrating OATP1B1/B3-dependent hepatocyte-specific uptake, the expression of OATP1B1/B3 being associated with the WNT-β-catenin signaling pathway [31], and the immune cell infiltration of the tumor microenvironment [32], it can be potentially used for evaluating the immune microenvironment status of HCC. This evidence concerns the gene SLCO1B1 and hepatocellular carcinoma.