Additionally, the presence of SP/NK-1R in the nucleus and cytoplasm of TC follicular cells aligns with findings in various human malignant neoplasms, such as keratocystic odontogenic tumors, gastric carcinoma, laryngeal squamous cell carcinoma, oral squamous cell carcinoma, small and nonsmall lung cancer, melanoma, and breast cancer [25,26,27,28,29,30,31,32,33]. The gene discussed is TACR1; the disease is cancer.