ADRB2 and obesity due to melanocortin 4 receptor deficiency: Numerous genetic variations linked to obesity-related asthma have been pinpointed in research studies, encompassing ADIPOQ [97,98], retinoid-related orphan receptor C (RORC), IL17A [99], TNF-α [100,101,102], beta-2 adrenergic receptor (ADRB2) [103], and IL-6 [104].