Intra-abdominal fat mass in normal-weight NIH-defined PCOS women is increased in proportion to circulating androgen concentrations and fasting levels of insulin, TG and non-high-density lipoprotein (non-HDL) cholesterol [59]; it also exhibits exaggerated catecholamine-induced lipolysis in non-obese PCOS women [81,82]. The gene discussed is INS; the disease is polycystic ovary syndrome.