FDFT1 and colorectal carcinoma: FDFT1 silencing obviously inhibited the tumor growth in both intraperitoneal implantation and subcutaneous xenograft models of CRC in C57BL/6 mice (p < 0.05), but the colorectal peritoneal metastasis model of NCG mice presented no difference in tumor growth after silencing FDFT1 (p > 0.05), suggesting that FDFT1 promoted the growth of CRC in vivo with dependence on the tumor immune microenvironment [29].