ATM and colorectal carcinoma: ATA has been previously reported to exhibit distinctive cytotoxicity towards tumor cells, including human ovarian carcinoma HO-8910 cells, cervical squamous carcinoma HeLa cells, leukemic HL-60 cells, colorectal carcinoma COLO-205 cells, and human hepatoma HepG2 cells [6,7,8], as well as to inhibit the growth of transplanted B16-F10 melanoma in mice [8].