TP53 and cancer: Regarding the other approach to autophagy in cancer cells, several studies have demonstrated that the autophagy pathway supplies tumor cells with nutrients [14,15], increases the survival of cancer cells and their resistance to stress factors [16], lowers p53 levels [17], favors tumor metabolism [18,19], inhibits the surface expression of MHC-I on cancer cells, protecting them from lymphocyte cytotoxicity [20], and promotes metastasis [21].