This has implications for the importance of CCR2 in drug discovery for a variety of pathologies, e.g., inflammatory and autoimmune diseases, such as rheumatoid arthritis [15], multiple sclerosis [16], and autoimmunity-driven type-1 diabetes [18], but also ischemic stroke [16], liver disease [19], asthma, atherosclerosis, transplant rejection [20], diabetic nephropathy, neuropathic pain, and the promotion of cancer cell metastasis [18]. Here, CCR2 is linked to cancer.