Low IGF-2R expressions had a poorer prognosis than those with high IGF-2R expressions -With ↓ expressions, PFS and OS are shorter (6.8 ± 2.1 vs. 8.8 ± 2.4, months, p < 0.001 and 11.1 ± 7.2 vs. 17.1 ± 2.8, months, p < 0.001)↓ Expressions are associated with later tumor stage (p = 0.0013) and poorer differentiation status (p < 0.001). The gene discussed is IGF2R; the disease is neoplasm.