RAP2C-AS1, which has been implicated in esophageal cancer [113], AQP4-AS1, while also being associated with retinal neurovascular dysfunction [114], possibly cancer [102], and DCTN1-AS1, potentially contributing to Alzheimer’s disease development [103], has undergone scarce investigations. The gene discussed is AQP4; the disease is early-onset autosomal dominant Alzheimer disease.