When examining potential latent interactions in terms dynamic interplay between virus-specific “target” antibodies and “adventitious” nAAbs, upon an aged antigenic trigger like childhood MMR vaccines or potential earlier natural measles, mumps, or rubella infections, interestingly, statistically significant connections have been revealed between the anti-CS IgM levels and the viral-antigen-specific (measles, mumps, rubella) IgG qualitative (positive, negative) results. The gene discussed is CD40LG; the disease is rubella.