LPA and atherosclerosis: A measurement of Lp(a) should be considered at least once in each person’s lifetime, if available, to identify persons who have inherited an increased (>50 mg/dL) or extremely high level of Lp(a) (>180 mg/dL) and who therefore have a very high lifetime risk of ASCVD, roughly equivalent to the risk associated with HeFH (heterozygous familial hypercholesterolemia).