UBE2N and invasive breast carcinoma: Results demonstrated that the gene AKT3 (0.88), which is significantly up-regulated in FTD, is significantly down-regulated in breast invasive carcinoma patients (Figure 2A), whereas the genes UBE2N (0.766) and VDAC1 (0.96) were significantly up-regulated in FTD are significantly up-regulated in breast invasive carcinoma patients also (Figure 2A).