We further explored the interaction between the FTD-Breast comorbid genes (AKT3, GFAP, C4A, VDAC1, ADCYAP1R1) and their different aspects of biological pathways in relation to neurological changes by finding the pathways on https://www.kegg.jp/kegg/pathway.html (accessed on 6 January 2023) [12]. This evidence concerns the gene C4A and frontotemporal dementia.