Overall, we found two novel FTD-COVID-19 comorbid genes, GFAP and RTN4, and five novel FTD-Breast cancer comorbid genes, AKT3, GFAP, ADCYAP1R1, VDAC1, and C4A, in this study. The gene discussed is ADCYAP1R1; the disease is frontotemporal dementia.