STING1 and head and neck squamous cell carcinoma: Baird et al. [56] initially attributed STING expression and activity in HNSCC to HPV status and the respective origin of the neoplastic cell population: STING expression in HPV-positive HNSCCs was related to their development from the STING-positive basaloid squamous epithelium, whereas HPV-negative HNSCCs arise from STING-negative differentiated keratinocytes of the epithelium.