IL1B and infection: We found that patients with a moderate/severe disease presented higher levels of MG-H1 (Figure 6a), RAGE (Figure 6b) and IL-1β (Figure 6d), and lower levels of Glo1 (Figure 6c) expression, compared with the non-severe group, thus strongly suggesting that the mechanistic in vitro core results, showing MG-H1/RAGE pathway as a novel SARS-CoV-2 S1-driven pro-inflammatory axis, might occur during infection.