Interestingly, there are 85 DE genes in module 2 that are also part of the GRN, 3 of them over-expressed in the control (CPNE5, PLIN1 and MYOC) and the other 82 in periodontitis, which are enriched in inflammatory response GO terms (Figure 5B and Figure A3B). The gene discussed is MYOC; the disease is periodontitis.