Such a function of histone deacetylase 2 in the processes of the migration and invasion of lung cancer cells can be implemented by regulating the expression of protein complexes, such as eukaryotic initiation factors 5 and 6 (eIF5 and eIF6), which play a decisive role in the occurrence and progression of tumors [314,315,316,317]. The gene discussed is HDAC2; the disease is lung cancer.