The increased expression of different types of collagen components such as collagen type I alpha 1 chain, collagen type IV alpha 5 chain, and collagen type XI alpha 2 chain, as well as CEA adhesion molecule 1, integrin subunits alpha 1 and 10, laminin subunits, and syndecan 1, indicated an attempt of tumor cells towards the formation of ECM connections between cancer cells and the environment, which could lead to invasion and metastasis. The gene discussed is SDC1; the disease is cancer.