DUSP6 and breast cancer: In the BC-treated Ztm male mice vs. Ztm control male mice, Nfkbiz was downregulated (log2 fold change of −1.02) with a significant q-value (7.17 × 10−5), Map2k7 was highly upregulated upon treatment with a log2 fold change of 5.02; App and Cd14 transcripts showed slight upregulation and downregulation, respectively; Dusp6 and Ppp2r1b were downregulated; and Creb1 and Atf2 showed dramatic downregulation, as seen with their massive negative fold changes.