Another oncogene overexpressed in various malignant tumors [101], such as GBM cells and serum [100] and CRC tissues and cell lines [102], ferritin light chain (FTL), interacts with PI3K/Akt, GADD45/JNK, TGF-β signaling, and cell cycle proteins. The gene discussed is GADD45A; the disease is colorectal carcinoma.