UBA1 and cancer: We identified 6 differentially expressed proteins (4 upregulated and 2 downregulated) related to JTBhigh condition vs. control that emphasize a pro-tumorigenic (PT) role (RBBP4, SET, ABRACL, NCKAP1, GSN, and PRDM5), while 21 proteins, which are known to be usually overexpressed in cancer cells, emphasized an anti-tumorigenic role when low expression occurs as happened in this experiment (UBA1, YWHAZ, TUBB2A, ITGB5, HSPB1, PCBP2, MCCC2, UGDH, TPI1, ATP5F1B, DLSI, FTL, HYOU1, PRDX6, NRDC1, and HNRNPK), as well as three ribosomal proteins (RPL7A, RPL31, and RPS3).