EDN1 and obstructive sleep apnea syndrome: We also investigated inflammatory markers related to cardiac damage and observed an increase in ET-1 levels in AMI patients, regardless of the presence of OSA: Control w/o OSA vs. AMI w/o OSA (1.83 ± 0.35 vs. 3.31 ± 1.42; p = 0.0005) and Control w/o OSA vs. AMI w OSA (3.31 ± 1.42 vs. 3.22 ± 2.10; p = 0.026).