GPX2 and neoplasm: We observed a significant correlation between high Gpx-2 expression and factors such as the histological grade of the tumour (p < 0.001, Chi2 test), depth of invasion (p = 0.001, Fisher’s exact test), angioinvasion (p < 0.001, Fisher’s exact test) and PCNA immunohistochemical expression (p < 0.001, Fisher’s exact test).