Interestingly, when cells were re-seeded and grown for 96 h in high glucose medium after FCCP exposure, colon carcinoma-derived IF1-expressing cells showed a significantly greater proliferation rate than IF1-silenced cells, while no differences were observed between osteosarcoma cells expressing or not expressing IF1 (Figure 11A,B). Here, ATP5IF1 is linked to colon carcinoma.