Examples of some voltage-gated ion channel genes associated with epilepsy include: SCN1A (encodes a voltage-gated Na+ channel subunit, NaV1.1), SCN2A (encodes a voltage-gated Na+ channel subunit, NaV1.2), KCNQ2 (voltage-gated K+ channel subunit, KV1.2), and CACNA1A (voltage-gated Ca2+ channel subunit, CaV2.1) [10]. The gene discussed is CACNA1A; the disease is epilepsy.