Another example is Dravet syndrome which is predominantly caused by variants in SCN1A, but other genes have also been associated with the syndrome, such as GABRA1, STXBP1, PCDH19 (females only), and GABRG2 [25,26,27,28]. The gene discussed is SCN1A; the disease is encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.