Moreover, studies performed on serum of patients revealed increased levels of a range of pro-inflammatory cytokines, such as TNF-α (tumor necrosis factor-α), interleukins IL-1β, IL-2, IL-10, or IL-17, as well as an increased number of T helper 1 cells, the authors also being able to link higher pro-inflammatory profiles with enhanced motor progression and cognitive decline [30,31]. The gene discussed is TNF; the disease is Mental deterioration.