TNF and cardiac hypertrophy: We found that the values of EF and FS in the heart of mice with myocardial hypertrophy were decreased, the activities of serum LDH and CK were increased, the deposition of myocardial collagen was increased, the levels of MDA, T-AOC, and T-SOD in myocardial tissue were increased, and the levels of serum IL-6 and TNF-α were elevated.