FOXP1 and acute myeloid leukemia: AML cells overexpressing SIRT1 via an inducible lentiviral vector were treated with increasing concentrations of daunorubicin, and FOXP1 activity protected AML cells against cytotoxic treatment; thus, the level of FOXP1 expression was correlated with increased resistance to daunorubicin in AML cells that overexpress SIRT1 [57].