CYCS and hepatocellular carcinoma: There was oxidative stress manifested as a decline in ΔΨmito, cytochrome c release, an increase in ROS generation, an increase in lipid peroxidation, a decrease in ATP and reduced glutathione, and a decrease in thioredoxin reductase and glutathione peroxidase activity in human hepatoma HepG2 cells, human neuroblastoma SH-SY5Y cells, human gingival fibroblasts, hamster pancreatic HIT-T15 β-cells, normal rat kidney cells, rat ascites hepatoma AS-30D cells, and human T cells and leukocytes [153,154,155,156,157,158,159,160,161,162].