It is reported that one of the most relevant consequences of overnutrition and obesity during early life is the development of insulin resistance [6], a condition associated with a decreased activation of the PI3K-Akt pathway in insulin-dependent tissues such as the liver skeletal muscle and adipose tissue, which results in an impaired uptake and storage of glucose, promoting hyperglycemia in the long term [13]. Here, AKT1 is linked to overnutrition.