Firstly, this approach has been shown to be effective in a mouse model of CeD [104,105], where intravenous infusion of gliadin-encapsulating nanoparticles inhibited the proliferation, and the IFN-γ and IL-17 secretion, of gliadin-specific T cells, while increasing the frequency of FoxP3+ Treg cells. The gene discussed is IL17A; the disease is cranioectodermal dysplasia.