MMP9 and metastatic malignant neoplasm in the lymph nodes: Furthermore, increased MMP-9 expression was associated with FIGO stage (OR = 4.85, 95 percent CI 2.60–9.04, P0.00001), grade of differentiation (OR = 3.34, 95 percent CI 2.46–4.54, P0.00001), lymph node metastasis (OR = 5.75, 95 percent CI 3.71–8.92, P0.00001), and there was no association with histological type of ovarian cancer [33].