POSTN + fibroblasts showed high expression levels of several ECM remodeling genes (MMP11, CTHRC1, COL1A1, COL1A2, COL3A1, COL10A1, and COL11A1) and enriched signatures of ECM (Fig. 2b and c; Table S4), which were consistent with the previously reported matrix CAFs (mCAFs) in cervical squamous cell carcinoma (CESC) [15]. The gene discussed is COL1A1; the disease is cervical squamous cell carcinoma.