We found there are six predictors of hypoglycemia during hemodialysis in the patients: hemodialysis duration 8 ~ 15 years, hemodialysis duration 16 ~ 21 years, having hypotension during last hemodialysis, having hyperglycemia on the latest hemodialysis night, disturbance of potassium metabolism, and serum albumin < 35 g/L. The gene discussed is ALB; the disease is Hyperglycemia.