Genes related to the cancer-associated adipocytes (CAA) phenotype were found induced, and these included the C–C motif chemokine ligand 2 (CCL2), interleukin-1 beta (IL-1B), and C-X-C motif chemokine ligand 8 (CXCL8) (Fig. 4A). Here, CCL2 is linked to cancer.