Serological markers of APS are antiphospholipid antibodies (aPLs), which, according to international classification criteria, include IgG/IgM antibodies to cardiolipin (aCL), IgG/IgM antibodies to β2-glycoprotein 1 (anti-β2GP1) and lupus anticoagulant (LA) [2]. The gene discussed is CD40LG; the disease is autoimmune polyendocrinopathy.