The CCK-8 tests demonstrated that Sorcin knockdown could decrease the cell proliferation ability of HCC cells when compared to the control group (25.38%, 40.06%, and 42.82% reduction in HCC-LM3 cells, 33.25%, 24.27%, and 25.23% reduction in HuH7 cells, respectively) (Fig. 2D, E). Here, SRI is linked to hepatocellular carcinoma.