CASP1 and hepatocellular carcinoma: Our results manifested that the inhibitory effects of Sorcin knockdown on HCC cell proliferation, migration, and invasion were reversed by using the Caspase-1 inhibitor VX765 and the NLRP3 inhibitor MCC950, further suggesting that Sorcin facilitates HCC progression by regulating NLRP3 inflammasome-mediated classical pyroptosis.