NLRP3 and hepatocellular carcinoma: Therefore, high expression of Sorcin in HCC cells might have a competitive binding Ca2+ with NLRP3 inflammasome, weakening the promotion effect of Ca2+ on NLRP3 inflammasome activation, inhibiting the activation and assembly of NLRP3 inflammasome, further preventing the activation of the natural immune response in vivo, and suppressing the immune protective effect of the body.