Additionally, transwell invasion assays confirmed that Sorcin knockdown potently suppressed cell invasion in HCC cells (74.77%, 67.56%, and 84.47% reduction in HCC-LM3 cells, 50.39%, 74.42%, and 66.67% reduction in HuH7 cells, compared with the control group, respectively (Fig. 2J, K). This evidence concerns the gene SRI and hepatocellular carcinoma.