CRP and obesity due to melanocortin 4 receptor deficiency: This result was consistent with a previous report showing that weight loss after bariatric surgery was negatively correlated with preoperative SFA and not VFA in Japanese patients with obesity.[17] Our results show that preoperative weight loss was associated with increased initial WBC count, lymphocyte count, and CRP levels, indicating that chronic inflammation inhibits medical weight management before surgery (Fig. 1).