This leads to a phosphorylation cascade that activates downstream pathways and regulates the occurrence and progression of tumors.[36] Therefore, the inhibitory effects of EH, Que, Lut and Wed on the expression of EGF-induced p-EGFR were tested to preliminarily evaluate the role of the active components in regulating breast cancer through EGFR-related signaling pathways. This evidence concerns the gene EGF and breast carcinoma.