As shown in Figure 10B, the 15 clusters are #0 Complementary therapies, #1 Cancer, #2 analgesia, #3 bee venom, #4 breast cancer, #5 acustimulation, #6 chronic pain, #7 neuropathic pain, #8 acupuncture, #9 aromatase inhibitors, #10 manual acupuncture, #11 integrative therapies, #12 therapy, #13 chemotherapy- induced peripheral neuropathy, #14 controlled clinical trial and #15 chronic cancer pain, which are the most discussed topics in the field. The gene discussed is CYP19A1; the disease is breast cancer.