VIM and cervical cancer: However, the upregulation of GFAP and Vimentin was independent of direct contact of cervical cancer cells with nerves, because the presence of PNI was not associated with any major change in immunoreactivity for GFAP [PNI(−): 60.57% ± 2.1%; PNI(+): 58.52% ± 1.87%; Figure 4A,B] or Vimentin [PNI(−): 48.41% ± 7.3%; PNI(+): 49.66% ± 7.4%; Figure 4A,B].