KLK3 and posterior cortical atrophy: Each year within the US,tests are performed on 13% of men aged 40–54 years and 39%of men aged 55–69 years.37 Screeningfor PCa is among the most controversial topics in the urological literature.Population-based PCa screening with PSA tests was widely adopted withinthe 1990s, which decreased mortality and also led to significant overdiagnosisand unnecessary treatment.