Although some dysregulations of neuropeptide signalling were massive in the old ATM-null mouse cerebellum and were very relevant for phenotypes of A-T—e.g., the increases in mRNA of growth hormone inhibitor somatostatin (Sst), vasodilator preprotachykinin (Tac1) and the tachykinin receptor (Tacr1), as well as the glutamate-excitability factor VGLUT2 (encoded by Slc17a6)—the SH-SY5Y neuroblastoma line did not express these genes. Here, TAC1 is linked to neuroblastoma.