It has been reported that macrophages harvested from Cd36-deficient mice are defective in oxLDL uptake, and Cd36-deficient mice with atherosclerosis-prone background, including LDL receptor-null and ApoE-null mice, fed with a high-fat diet showed less atherosclerotic lesion formation compared to the control [18,93,94]. Here, LDLR is linked to atherosclerosis.