Under hypoxic conditions, granulocytic MDSC (G‐MDSC)‐derived exosomes carrying S100A9 proteins can promote cancer stemness in murine CT26 colon cancer cells and azoxymethane/dextran sodium sulfate (AOM/DSS)‐induced colon cancer.106. The gene discussed is S100A9; the disease is malignant colon neoplasm.