If measured:-Apolipoprotein B levels with elevations >130 mg/dl (may be useful if hypertriglyceridemia >200 mg/dl to rule out genetic disorders such as type III hyperlipoproteinemia or to clarify ASCVD risk)-High-sensitivity C-reactive protein ≥2 mg/L-Lipoprotein(a) levels with elevations >50 mg/dl (>125 nmol/L). Elevated lipoprotein(a) levels may be especially useful in those with a family history of ASCVD-Ankle-brachial index <0.90 The gene discussed is APOB; the disease is atherosclerosis.